Integration of High-Resolution Radiation Detector for Hybrid Microchip Electrophoresis.

ABSTRACT: For decades, there has been immense progress in miniaturizing analytical methods based on electrophoresis to improve sensitivity and to reduce sample volumes, separation times, and/or equipment cost and space requirements, in applications ranging from analysis of biological samples to environmental analysis to forensics. In the field of radiochemistry, where radiation-shielded laboratory space is limited, there has been great interest in harnessing the compactness, high efficiency, and speed of microfluidics to synthesize short-lived radiolabeled compounds. We recently proposed that analysis of these compounds could also benefit from miniaturization and have been investigating capillary electrophoresis (CE) and hybrid microchip electrophoresis (hybrid-MCE) as alternatives to the typically

SUBMITTER: Jones J 

PROVIDER: S-EPMC7410349 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature