Using the Ultrasensitive Alere Plasmodium falciparum Malaria Ag HRP-2^™ Rapid Diagnostic Test in the Field and Clinic in Northeastern Uganda.

ABSTRACT: The ultrasensitive Alere Plasmodium falciparum Malaria Ag histidine-rich protein 2 rapid diagnostic test (Alere uRDT, Suwon City, South Korea) is a new diagnostic tool which is more expensive than other malaria rapid diagnostic tests (RDTs) routinely used in Ugandan clinics. The manufacturer recommends testing samples within 2 days and scoring results after 20 minutes, which may be impractical in high-volume resource-poor clinics. We compared testing by the Alere Ag rapid diagnostic test (uRDT), CareStart RDT, microscopy, and an ultrasensitive I8S rRNA quantitative reverse transcription polymerase chain reaction (qRT-PCR) using survey and clinical samples. For the Alere uRDT, we used survey blood samples stored at 4°C for 44 days and for some clinical samples deliberately scored res

SUBMITTER: Owalla TJ 

PROVIDER: S-EPMC7410421 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature