The Use of Factorial Design and Simplex Optimization to Improve Analytical Performance of In Situ Film Electrodes.

ABSTRACT: This work presents a systematic approach to determining the significance of the individual factors affecting the analytical performance of in-situ film electrode (FE) for the determination of Zn(II), Cd(II), and Pb(II). Analytical parameters were considered simultaneously, where the lowest limit of quantification, the widest linear concentration range, and the highest sensitivity, accuracy, and precision of the method evidenced a better analytical method. Significance was evaluated by means of a fractional factorial (experimental) design using five factors, i.e., the mass concentrations of Bi(III), Sn(II), and Sb(III), to design the in situ FE, the accumulation potential, and the accumulation time. Next, a simplex optimization procedure was employed to determine the optimum conditions for

SUBMITTER: Finsgar M 

PROVIDER: S-EPMC7411898 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature