Evaluation of Overall Survival in Patients With Anaplastic Thyroid Carcinoma, 2000-2019.

ABSTRACT:

Importance

Anaplastic thyroid carcinoma (ATC) historically has a 4-month median overall survival (OS) from time of diagnosis, with disease-specific mortality approaching 100%. The association between recent major advancements in treatment and OS has yet to be evaluated.

Objective

To evaluate rates of OS in patients with ATC over the last 2 decades.

Design, setting, and participants

Retrospective cohort study in a single tertiary care institution. Patients with histopathological confirmation of ATC from January 2000 to October 2019 were included and divided into 3 groups according to date of presentation: 2000-2013, 2014-2016, and 2017-2019.

Main outcomes and measures

Overall survival compared among different treatment eras and differing therapies, including tar

SUBMITTER: Maniakas A 

PROVIDER: S-EPMC7411939 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature