Preclinical Study of a Multi-Layered Antimicrobial Patch Based on Thin Nanocomposite Amorphous Diamond Like Carbon Films with Embedded Silver Nanoparticles.

ABSTRACT: A growing number of severe infections are related to antibiotic-resistant bacteria, therefore, in recent years, alternative antimicrobial materials based on silver nanoparticles (NPs) attracted a lot of attention. In the current research, we present a medical patch prototype containing diamond-like carbon nanocomposite thin films doped with silver nanoparticles (DLC:Ag), as a source of silver ions, and an aqueous mass of the gelatin/agar mixture as a silver ion accumulation layer. The DLC:Ag thin films with 3.4 at.% of silver were deposited on synthetic silk employing reactive unbalanced DC magnetron sputtering of the silver target with argon ions performed in the acetylene gas atmosphere. The average size of the silver nanoparticles as defined by scanning electron microscope was 24 nm. Af

SUBMITTER: Juknius T 

PROVIDER: S-EPMC7412193 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature