Quasi-Isostructural Co(II) and Ni(II) Complexes with Mefenamato Ligand: Synthesis, Characterization, and Biological Activity.

ABSTRACT: Three metal complexes of mefenamato ligand 1 were synthesized: [Co₂(mef)₄(EtOH)₂(H₂O)₄]: 2; [Co(mef)₂(MeOH)₄]∙2MeOH: 3; and [Ni(mef)₂(MeOH)₄]∙2MeOH: 4. Their compositions and properties were investigated by elemental analysis (EA), flame atomic absorption spectrometry (FAAS), Fourier-transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA). Crystal structures were determined by the single crystal X-ray diffraction technique. Additionally, their antioxidant and antimicrobial activity were established, thus proving good/moderate bioactivity against Gram-positive bacteria and yeasts. In the crystal structure of 2, an apical water molecule is

SUBMITTER: Gacki M 

PROVIDER: S-EPMC7412345 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature