A Biocompatible, Stimuli-Responsive, and Injectable Hydrogel with Triple Dynamic Bonds.

ABSTRACT: Injectable hydrogels have attracted growing interests as promising biomaterials for clinical applications, due to their minimum invasive implanting approach and easy-handling performance. Nevertheless, natural biomaterials-based injectable hydrogels with desirable nontoxicity are suffering from limited functions, failing to fulfill the requirements of clinical biomaterials. The development of novel injectable biomaterials with a combination of biocompatibility and adequate functional properties is a growing urgency toward biomedical applications. In this contribution, we report a simple and effective approach to fabricate multi-functional CMC-OSA-DTP hydrogels. Two kinds of natural polysaccharide derived polymers, carboxymethyl chitosan (CMC) and oxidized alginate (OSA) along with 3,3'-dit

SUBMITTER: Chen Y 

PROVIDER: S-EPMC7412394 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature