Developing a crosswalk between the RAND-12 and the health utilities index for multiple sclerosis.

ABSTRACT:

Background

Researchers studying health-related quality of life (HRQOL) in multiple sclerosis (MS) can choose from many instruments, but findings from studies which use different instruments cannot be easily combined. We aimed to develop a crosswalk that associates scores from the RAND-12 to scores on the Health Utilities Index-Mark III (HUI3) in persons with MS.

Methods

In 2018, participants in the North American Research Committee on Multiple Sclerosis (NARCOMS) registry completed the RAND-12 and the HUI3 to assess HRQOL. We used item-response theory (IRT) and equipercentile linking approaches to develop a crosswalk between instruments. We compared predicted scores for the HUI3 from each crosswalk to observed scores using Pearson correlations, intraclass correlation coeffic

SUBMITTER: Marrie RA 

PROVIDER: S-EPMC7412875 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature