Fabrication of the Composite Regenerative Peripheral Nerve Interface (C-RPNI) in the Adult Rat.

ABSTRACT: Recent advances in neuroprosthetics have enabled those living with extremity loss to reproduce many functions native to the absent extremity, and this is often accomplished through integration with the peripheral nervous system. Unfortunately, methods currently employed are often associated with significant tissue damage which prevents prolonged use. Additionally, these devices often lack any meaningful degree of sensory feedback as their complex construction dampens any vibrations or other sensations a user may have previously depended on when using more simple prosthetics. The composite regenerative peripheral nerve interface (C-RPNI) was developed as a stable, biologic construct with the ability to amplify efferent motor nerve signals while providing simultaneous afferent sensory feedba

SUBMITTER: Svientek SR 

PROVIDER: S-EPMC7413224 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature