Memory reconsolidation as a tool to endure encoding deficits in elderly.

ABSTRACT: Normal aging involves changes in the ability to acquire, consolidate and recall new information. It has been recently proposed that the reconsolidation process is also affected in older adults. Reconsolidation is triggered after reminder presentation, allowing memories to be modified: they can be impaired, strengthened or changed in their content. In young adults it was previously shown that the presentation of repetitive reminders induces memory strengthening one day after reactivation and the presentation of at least one reminder increases memory persistence several days after reactivation. However, until now this process has remained elusive in older adults. We hypothesize that older adults need a stronger reminder to induce memory strengthening through the reconsolidation process than

SUBMITTER: Tassone LM 

PROVIDER: S-EPMC7413497 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature