What is needed to achieve HCV microelimination among HIV-infected populations in Andalusia, Spain: a modeling analysis.

ABSTRACT:

Background

Scale-up of hepatitis C virus (HCV) treatment for HIV/HCV coinfected individuals is occurring in Spain, the vast majority (> 85%) with a reported history of injecting drug use and a smaller population of co-infected men who have sex with men (MSM). We assess impact of recent treatment scale-up to people living with HIV (PLWH) and implications for achieving the WHO HCV incidence elimination target (80% reduction 2015-2030) among PLWH and overall in Andalusia, Spain, using dynamic modeling.

Methods

A dynamic transmission model of HCV/HIV coinfection was developed. The model was stratified by people who inject drugs (PWID) and MSM. The PWID component included dynamic HCV transmission from the HCV-monoinfected population. The model was calibrated to Andalusia based on

SUBMITTER: Skaathun B 

PROVIDER: S-EPMC7414743 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature