Estimating the potential for dementia prevention through modifiable risk factors elimination in the real-world setting: a population-based study.

ABSTRACT:

Background

Preventing dementia onset is one of the global public health priorities: around 35% of dementia cases could be attributable to modifiable risk factors. These estimates relied on secondary data and did not consider the concurrent effect of non-modifiable factors and death. Here, we aimed to estimate the potential reduction of dementia incidence due to modifiable risk factors elimination, controlling for non-modifiable risk factors and for the competing risk of death.

Methods

Participants from the InveCe.Ab population-based prospective cohort (Abbiategrasso, Italy) without a baseline dementia diagnosis and attending at least one follow-up visit were included (N = 1100). Participants underwent multidimensional assessment at baseline and after 2, 4, and 8 years, from

SUBMITTER: Rolandi E 

PROVIDER: S-EPMC7414752 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature