Two-Dimensional Analysis of Horizontal and Vertical Pursuit in Infantile Nystagmus Reveals Quantitative Deficits in Accuracy and Precision.

ABSTRACT:

Purpose

Infantile nystagmus (IN) presents with continuous, predominantly horizontal eye oscillations. It remains controversial whether those with IN have normal horizontal pursuit, while vertical pursuit has rarely been studied. We examined whether there are pursuit deficits associated with IN by investigating the effect of target direction, velocity, and amplitude.

Methods

Twelve adults with idiopathic IN performed a pursuit task, a 0.4° dot moved either horizontally or vertically at 8 or 16°/s, through amplitudes of 8°, 16°, or 32°. Accuracy and precision errors were computed as bivariate probability density functions of target-relative eye velocities.

Results

Eye velocity was less precise along the horizontal axis during both horizontal and vertical pursuit, reflec

SUBMITTER: Mcilreavy L 

PROVIDER: S-EPMC7415281 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature