Changes in body weight, adherence, and appetite during 2 years of calorie restriction: the CALERIE 2 randomized clinical trial.

ABSTRACT:

Background/objectives

The Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy Phase 2 (CALERIE) study showed that individuals who are nonobese were able to undergo significant calorie restriction (CR), yet the time course changes in adherence, weight, and appetite are unknown. This analysis aimed to investigate the time course changes in adherence, body weight, and appetite during the CALERIE study.

Subjects/methods

Overall, 143 participants (body mass index: 21.9-28.0 kg/m²) were randomized to a CR group that aimed to achieve 25% CR for 2 years. Throughout the intervention, body weight was measured, and appetite was assessed through visual analogue scales. Algorithms were utilized with body weight measurements to calculate adherence percent

SUBMITTER: Dorling JL 

PROVIDER: S-EPMC7415503 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature