Periodontal Disease, Tooth Loss, and Risk of Serrated Polyps and Conventional Adenomas.

ABSTRACT: Growing data indicate an association between periodontal disease and the development of cancer. However, the evidence for colorectal cancer has been inconsistent and longitudinal study examining its precursor lesions is lacking. We prospectively collected information on periodontal disease and number of tooth loss in the Nurses' Health Study (1992-2002) and the Health Professionals Follow-up Study (1992-2010). Polyp diagnosis was acquired via self-reported questionnaires and confirmed through review of medical records. We used logistic regression to calculate the multivariate-adjusted ORs and 95% confidence intervals (CI) with adjustment for smoking and other known risk factors for periodontal disease and colorectal cancer. In this study, we included 17,904 women and 24,582 men. We documen

SUBMITTER: Lo CH 

PROVIDER: S-EPMC7415594 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature