Antenatal Corticosteroids for Pregnant Women at High Risk of Preterm Delivery with COVID-19 Infection: A Decision Analysis.

ABSTRACT:

Objective

Antenatal corticosteroids given prior to preterm deliveries reduce the risk of adverse neonatal outcomes. However, steroid administration in the setting of a viral respiratory infection can worsen maternal outcomes. Therefore, the decision to administer corticosteroids must balance the neonatal benefits with the potential harm to the mother if she is infected with the novel coronavirus disease 2019 (COVID-19). This study aimed to determine the gestational ages for which administering antenatal corticosteroids to women at high risk of preterm labor with concurrent COVID-19 infection results in improved combined maternal and infant outcomes.

Study design

A decision-analytic model using TreeAge (2020) software was constructed for a theoretical cohort of hospitalized w

SUBMITTER: Packer CH 

PROVIDER: S-EPMC7416210 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature