Better programmatic outcome with the shorter regimen for the treatment of multidrug-resistant tuberculosis (MDR-TB) in Guinea: A retrospective cohort study.

ABSTRACT:

Setting

Since August 2016, after the Ebola outbreak, the Guinean National Tuberculosis Programme and Damien Foundation implemented the shorter treatment regimen (STR) for multidrug-resistant tuberculosis (MDR-TB) in the three MDR-TB sites of Conakry. Previously, the longer regimen was used to treat MDR-TB.

Objectives

In a post-Ebola context, with a weakened health system, we describe the MDR-TB treatment uptake, patients characteristics, treatment outcomes and estimate the effect of using the longer versus STR on having a programmatically adverse outcome.

Design

This is a retrospective cohort study in RR-TB patients treated with either the longer regimen or STR.

Results

In Conakry, in 2016 and 2017, 131 and 219 patients were diagnosed with rifampicin-resistant

SUBMITTER: Hassane-Harouna S 

PROVIDER: S-EPMC7416929 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature