Association of Opioid Prescription Initiation During Adolescence and Young Adulthood With Subsequent Substance-Related Morbidity.

ABSTRACT:

Importance

Concerns about adverse outcomes associated with opioid analgesic prescription have led to major guideline and policy changes. Substantial uncertainty remains, however, regarding the association between opioid prescription initiation and increased risk of subsequent substance-related morbidity.

Objective

To examine the association of opioid initiation among adolescents and young adults with subsequent broadly defined substance-related morbidity.

Design, setting, and participants

This cohort study analyzed population-register data from January 1, 2007, to December 31, 2013, on Swedish individuals aged 13 to 29 years by January 1, 2013, who were naive to opioid prescription. To account for confounding, the analysis compared opioid prescription recipients with

SUBMITTER: Quinn PD 

PROVIDER: S-EPMC7418042 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature