Impact of a vaccine intervention on county-level rates of acute hepatitis B in West Virginia, 2011-2018.

ABSTRACT: The rate of acute hepatitis B in West Virginia (WV) has been increasing since 2006. To reduce new infections, WV implemented a vaccine intervention (WV Pilot Project), which provided over 10,000 doses of hepatitis B vaccine to at-risk adults in 18 counties. The objectives of this study were to describe yearly changes in acute hepatitis B incidence and assess county-level impact of the WV Pilot Project using geospatial methods. County rates of acute hepatitis B and vaccine doses per 100,000 population were visualized biannually from 2011 to 2018. Local indicators of spatial autocorrelation were used to detect county-level clustering. Significant differences in the median rate of acute hepatitis B pre and post intervention in counties receiving vaccine were evaluated using Wilcoxon signed-ra

SUBMITTER: Tressler SR 

PROVIDER: S-EPMC7418051 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature