Prognosis and Management of BRAF V600E-Mutated Pregnancy-Associated Melanoma.

ABSTRACT:

Background

Approximately one third of women who develop melanoma at childbearing age are diagnosed during gestation or the postpartum period, facing pregnancy-associated melanoma (PAM). However, only some retrospective studies with heterogeneous data have analyzed the impact of pregnancy on melanoma development, and no evidence exists about the behavior and the management of BRAF-mutated disease.

Subjects, materials, and methods

In order to better describe the evolution of BRAF V600E-mutated PAM, we present here all consecutive cases diagnosed in our site during the last 7 years, recording oncological, obstetrical, and perinatal parameters, as well as the therapeutic decisions for both melanoma and gestation. Based on our institutional experience, we weigh the current publis

SUBMITTER: Ziogas DC 

PROVIDER: S-EPMC7418358 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature