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The burden of exacerbations in mild asthma: a systematic review.


ABSTRACT:

Background

Although most patients with asthma have mild disease, data on how mild asthma is defined, and how frequently exacerbations occur in this patient population are scarce, so we aimed to redress this.

Methods

We searched Medline and Medline In-Process (PubMed), and Embase in OVID for English-language publications containing "mild asthma" plus at least one relevant therapy and outcome/keyword, limited to randomised controlled trials (RCTs) and observational studies published between January 1990 and February 2019. Publications were filtered to ensure appropriate data extraction. The main outcomes were the definitions of mild asthma and exacerbations, baseline exacerbation rates and exacerbation data for placebo recipients in prospective studies. Meta-analysis of exacer

SUBMITTER: FitzGerald JM 

PROVIDER: S-EPMC7418821 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature