Transcriptome dataset for RNA-seq analysis of axolotl embryonic oropharyngeal endoderm explants.

ABSTRACT: Animal nutrition and toxin deterrence rely on the ability to taste, which occurs through columnar taste cells clustered within taste buds. Taste buds in mammals are located within specialized tissues, called papillae. However, taste buds in fish and amphibians, such as axolotls (Ambystoma mexicanum), are not housed in papillae, rather they are embedded within the pharyngeal epithelium. This simplified tissue level organization, along with the ability of cultured oropharyngeal explants from early embryos to produce taste buds on the same time-line as embryos, make the axolotl an excellent model to identify molecules specifically involved in taste bud cell differentiation. We performed de novo transcriptomic analysis on RNA sequences from three different stages of oropharyngeal explan

SUBMITTER: Marazzi L 

PROVIDER: S-EPMC7419325 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature