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Venous thromboembolism in patients with COVID-19: Systematic review and meta-analysis.


ABSTRACT:

Background

Venous thromboembolism (VTE) may complicate the course of Coronavirus Disease 2019 (COVID-19).

Objectives

To evaluate the incidence of VTE in patients with COVID-19.

Methods

MEDLINE, EMBASE, and PubMed were searched up to 24th June 2020 for studies that evaluated the incidence of VTE, including pulmonary embolism (PE) and/or deep vein thrombosis (DVT), in patients with COVID-19. Pooled proportions with corresponding 95% confidence intervals (CI) and prediction intervals (PI) were calculated by random-effect meta-analysis.

Results

3487 patients from 30 studies were included. Based on very low-quality evidence due to heterogeneity and risk of bias, the incidence of VTE was 26% (95% PI, 6%-66%). PE with or without DVT occurred in 12% of patients (95% PI

SUBMITTER: Porfidia A 

PROVIDER: S-EPMC7420982 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature