Ontology highlight
ABSTRACT:
SUBMITTER: Jovanovic T
PROVIDER: S-EPMC7421882 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Jovanovic Tanja T Stenson Anaïs F AF Thompson Nadia N Clifford Aimee A Compton Alisha A Minton Sean S van Rooij Sanne J F SJF Stevens Jennifer S JS Lori Adriana A Nugent Nicole N Gillespie Charles F CF Bradley Bekh B Ressler Kerry J KJ
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20200626 10
Dysregulated fear conditioned responses have been associated with PTSD in adults, with increased fear-potentiated startle (FPS) serving as a potential intermediate phenotype for PTSD risk. This phenotype has also been associated with stress-related ADCYAP1R1 gene variants in adult women. However, FPS and genotype have not yet been examined during development. The aim of this study was to examine developmental changes in fear conditioning, and to see whether these changes were impacted by genotyp ...[more]