Association between Inflammatory Bowel Disease and Pancreatitis: A PRISMA-Compliant Systematic Review.

ABSTRACT:

Methods

MEDLINE, Embase, and CENTRAL were systematically searched for correlative studies till 2 November 2019. RevMan5.3 was used to estimate relevance.

Results

Three studies with 166008 participants were included. The risk of pancreatitis significantly increased in the patients with CD (OR, 3.40; 95% CI, 2.70-4.28; P < 0.00001) and UC (OR, 2.49; 95% CI, 1.91-3.26; P < 0.00001). Increased risks of CD (OR, 12.90; 95% CI, 5.15-32.50; P < 0.00001) and UC (OR, 2.80; 95% CI, 1.00-7.86; P = 0.05) were found in patients with chronic pancreatitis. As for patients with acute pancreatitis, there were significant association of CD (OR, 3.70; 95% CI, 1.90-7.60; P = 0.0002), but were not UC.

Conclusions

The evidence confirmed an association betw

SUBMITTER: Li P 

PROVIDER: S-EPMC7422476 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature