Ontology highlight
ABSTRACT:
SUBMITTER: Lopez-Campos F
PROVIDER: S-EPMC7422545 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
López-Campos Fernando F Martín-Martín Margarita M Fornell-Pérez Roberto R García-Pérez Juan Carlos JC Die-Trill Javier J Fuentes-Mateos Raquel R López-Durán Sergio S Domínguez-Rullán José J Ferreiro Reyes R Riquelme-Oliveira Alejandro A Hervás-Morón Asunción A Couñago Felipe F
World journal of gastroenterology 20200801 29
According to the main international clinical guidelines, the recommended treatment for locally-advanced rectal cancer is neoadjuvant chemoradiotherapy followed by surgery. However, doubts have been raised about the appropriate definition of clinical complete response (cCR) after neoadjuvant therapy and the role of surgery in patients who achieve a cCR. Surgical resection is associated with significant morbidity and decreased quality of life (QoL), which is especially relevant given the favourabl ...[more]