Expression Profiles of Inflammatory Cytokines in the Aqueous Humor of Children after Congenital Cataract Extraction.

ABSTRACT:

Purpose

To investigate the change in cytokine microenvironment of the aqueous humor (AH) after surgery in children with congenital or developmental cataracts.

Methods

AH samples were obtained from 59 eyes diagnosed with a congenital or developmental cataract. Thirty-three of these eyes were aphakic following previous cataract surgery and were scheduled for secondary intraocular lens (IOL) implantation. Additionally, AH samples from 26 eyes that had not undergone surgery were taken. AH samples were then analyzed for 16 different inflammatory immune mediators using multiplex bead immunoassays and enzyme-linked immunosorbent assay (ELISA).

Results

The mean interval between secondary IOL implantation and original cataract surgery was 24.85 months (range, 9-60 months). Lev

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC7422780 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature