Short-Term Changes in Tear Lipid Layer Thickness After Instillation of Lipid Containing Eye Drops.

ABSTRACT:

Purpose

Lipid-containing eye drops is increasingly popular in eye clinics to treat dry eye. Tear lipid layer thickness (LLT) changes after instillation of lipid eye drops have not been characterized. We aim to evaluate these changes of LLT using a noninvasive interferometry-based method.

Methods

This prospective clinical study was conducted on staff and patients from Singapore National Eye Centre with ad hoc recruitment. Noninvasive tear break up time was measured using the Keratographer 5M. LLTs were measured using a tear interferometer machine before and at 1, 5, and 15 minutes after instillation of lipid-containing drops, either Cationorm unidose or Artelac Lipids. Fluorescein clearance (tear clearance rate) and Schirmer tests were conducted. The tear clearance rate of fl

SUBMITTER: Lim P 

PROVIDER: S-EPMC7422789 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature