Age-based differences in the diagnosis and management of esophageal eosinophilia.

ABSTRACT:

Background

Eosinophilic esophagitis (EoE) is hallmarked by esophageal eosinophilia, >15 eosinophils(eos)/high-powered field (hpf), unresponsive to acid inhibition, and varied symptomatology. EoE consensus guidelines do not discriminate based on age for initiating treatment.

Objective

To evaluate if age-related differences exist in managing esophageal eosinophilia and EoE within a university population.

Methods

In a retrospective cohort study from a referral center, the medical records of 426 pediatric and adult patients with at least 1 presenting symptom of esophagitis, reflux, or upper gastrointestinal dysfunction, who underwent esophageal biopsy between 2009 and 2011 were analyzed for age-based differences in care in diagnosing and managing esophageal eosinophilia.<

SUBMITTER: Rassbach W 

PROVIDER: S-EPMC7423520 | biostudies-literature | 2015 Jan-Feb

REPOSITORIES: biostudies-literature