Bone density, microarchitecture and strength estimates in white versus African American youth with obesity.

ABSTRACT:

Background

African Americans (AA) have more favorable bone density and microarchitecture compared to Whites (W), which may explain their observed lower fracture rates. Obesity has deleterious effects on bone microarchitecture and strength estimates and is associated with an increase in fracture risk. Adolescence and young adulthood are periods of active bone accrual and also periods characterized by an increasing prevalence of obesity. The effect of obesity on the relationship between race and bone parameters remains unclear, particularly in youth.

Objective

To assess differences in BMD, bone microarchitecture and strength estimates in AA and W adolescents and young adults with moderate to severe obesity. We hypothesized that racial differences in bone endpoints in lean yout

SUBMITTER: Campoverde Reyes KJ 

PROVIDER: S-EPMC7423738 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature