ProteoViz: a tool for the analysis and interactive visualization of phosphoproteomics data.

ABSTRACT: Quantitative proteomics generates large datasets with increasing depth and quantitative information. With the advance of mass spectrometry and increasingly larger data sets, streamlined methodologies and tools for analysis and visualization of phosphoproteomics are needed both at the protein and modified peptide levels. To assist in addressing this need, we developed ProteoViz, which includes a set of R scripts that perform normalization and differential expression analysis of both the proteins and enriched phosphorylated peptides, and identify sequence motifs, kinases, and gene set enrichment pathways. The tool generates interactive visualization plots that allow users to interact with the phosphoproteomics results and quickly identify proteins and phosphorylated peptides of interest for

SUBMITTER: Storey AJ 

PROVIDER: S-EPMC7423749 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature