Trajectory and early predictors of apathy development in first-episode psychosis and healthy controls: a 10-year follow-up study.

ABSTRACT: Apathy is prevalent in first-episode psychosis (FEP) and associated with reduced global functioning. Investigations of the trajectory of apathy and its early predictors are needed to develop new treatment interventions. We here measured the levels of apathy over the first 10 years of treatment in FEP and in healthy controls (HC). We recruited 198 HC and 198 FEP participants. We measured apathy with the Apathy Evaluation Scale, self-report version, psychotic symptoms with the Positive and Negative Syndrome Scale, depression with the Calgary Depression Scale for Schizophrenia, functioning with the Global Assessment of Functioning Scale, and also estimated the duration of untreated psychosis (DUP). The longitudinal development of apathy and its predictors were explored using linear mixed mode

SUBMITTER: Lyngstad SH 

PROVIDER: S-EPMC7423800 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature