Risk of New Bloodstream Infections and Mortality Among People Who Inject Drugs With Infective Endocarditis.

ABSTRACT:

Importance

People who inject drugs (PWID) who are being treated for infective endocarditis remain at risk of new bloodstream infections (BSIs) due to ongoing intravenous drug use (IVDU).

Objectives

To characterize new BSIs in PWID receiving treatment for infective endocarditis, to determine the clinical factors associated with their development, and to determine whether new BSIs and treatment setting are associated with mortality.

Design, setting, and participants

This retrospective cohort study was performed at 3 tertiary care hospitals in London, Ontario, Canada, from April 1, 2007, to March 31, 2018. Participants included a consecutive sample of all PWID 18 years or older admitted with infective endocarditis. Data were analyzed from April 1, 2007, to June 29, 2018.

SUBMITTER: Tan C 

PROVIDER: S-EPMC7424403 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature