Principles of computer-controlled linear motion applied to an open-source affordable liquid handler for automated micropipetting.

ABSTRACT: OTTO is an open-source automated liquid handler that can be fabricated at a cost of $1,500 using off-the-shelf and 3D-printable parts as an alternative to commercial devices. Open-source approaches have been applied to build syringe pumps, centrifuges, and other laboratory equipment. These devices are affordable but generally rely on a single motor to perform simple operations and thus do not fully utilize the potential of the Maker Movement. Open-source linear actuators and microcontrollers enable the fabrication of more complex laboratory instruments that rely on 3D positioning and accurate dispensing of fluids, such as automated liquid handlers. These instruments can be built rapidly and affordably, thereby providing access to highly reproducible sample preparation for common biological

SUBMITTER: Florian DC 

PROVIDER: S-EPMC7424513 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature