Proteomic study of hypothalamus in pigs exposed to heat stress.

ABSTRACT:

Background

With evidence of warming climates, it is important to understand the effects of heat stress in farm animals in order to minimize production losses. Studying the changes in the brain proteome induced by heat stress may aid in understanding how heat stress affects brain function. The hypothalamus is a critical region in the brain that controls the pituitary gland, which is responsible for the secretion of several important hormones. In this study, we examined the hypothalamic protein profile of 10 pigs (15 ± 1 kg body weight), with five subjected to heat stress (35 ± 1 °C; relative humidity = 90%) and five acting as controls (28 ± 3 °C; RH = 90%).

Result

The isobaric tags for relative and absolute quantification (iTRAQ) analysis of the hypothalamus identified 1710 p

SUBMITTER: Yu TY 

PROVIDER: S-EPMC7424663 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature