Differences between predicted outer membrane proteins of genotype 1 and 2 Mannheimia haemolytica.

ABSTRACT:

Background

Mannheimia haemolytica strains isolated from North American cattle have been classified into two genotypes (1 and 2). Although members of both genotypes have been isolated from the upper and lower respiratory tracts of cattle with or without bovine respiratory disease (BRD), genotype 2 strains are much more frequently isolated from diseased lungs than genotype 1 strains. The mechanisms behind the increased association of genotype 2 M. haemolytica with BRD are not fully understood. To address that, and to search for interventions against genotype 2 M. haemolytica, complete, closed chromosome assemblies for 35 genotype 1 and 34 genotype 2 strains were generated and compared. Searches were conducted for the pan genome, core genes shared between the genotypes, and for genes

SUBMITTER: Clawson ML 

PROVIDER: S-EPMC7424683 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature