Forensic Autosomal Short Tandem Repeats and Their Potential Association With Phenotype.

ABSTRACT: Forensic DNA profiling utilizes autosomal short tandem repeat (STR) markers to establish identity of missing persons, confirm familial relations, and link persons of interest to crime scenes. It is a widely accepted notion that genetic markers used in forensic applications are not predictive of phenotype. At present, there has been no demonstration of forensic STR variants directly causing or predicting disease. Such a demonstration would have many legal and ethical implications. For example, is there a duty to inform a DNA donor if a medical condition is discovered during routine analysis of their sample? In this review, we evaluate the possibility that forensic STRs could provide information beyond mere identity. An extensive search of the literature returned 107 articles associating a f

SUBMITTER: Wyner N 

PROVIDER: S-EPMC7425049 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature