Development and preliminary validation of the Behcet's syndrome Overall Damage Index (BODI).

ABSTRACT:

Objective

To develop and validate the evidence-based and consensus-based Behçet's Syndrome Overall Damage Index (BODI).

Methods

Starting from 120 literature-retrieved preliminary items, the BODI underwent multiple Delphi rounds with an international multidisciplinary panel consisting of rheumatologists, internists, ophthalmologists, neurologists, and patient delegates until consensus was reached on the final content. The BODI was validated in a cross-sectional multicentre cohort of 228 patients with Behçet's syndrome (BS) through the study of (a) correlation between BODI and Vasculitis Damage Index (VDI) and (b) correlation between BODI and disease activity measures (ie, Behçet's Disease Current Activity Form (BDCAF), Physician Global Assessment (PGA), Patient Global Assessm

SUBMITTER: Piga M 

PROVIDER: S-EPMC7425117 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature