Kurtosis and skewness of high-frequency brain signals are altered in paediatric epilepsy.

ABSTRACT: Intracranial studies provide solid evidence that high-frequency brain signals are a new biomarker for epilepsy. Unfortunately, epileptic (pathological) high-frequency signals can be intermingled with physiological high-frequency signals making these signals difficult to differentiate. Recent success in non-invasive detection of high-frequency brain signals opens a new avenue for distinguishing pathological from physiological high-frequency signals. The objective of the present study is to characterize pathological and physiological high-frequency signals at source levels by using kurtosis and skewness analyses. Twenty-three children with medically intractable epilepsy and age-/gender-matched healthy controls were studied using magnetoencephalography. Magnetoencephalographic data in three f

SUBMITTER: Xiang J 

PROVIDER: S-EPMC7425348 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature