Association of Birth Weight with Peripapillary Retinal Nerve Fiber Layer Thickness in Adulthood-Results from a Population-Based Study.

ABSTRACT:

Purpose

Low birth weight is associated with altered retinal development in childhood, including reduced peripapillary retinal nerve fiber layer (pRNFL) thickness. However, to the best of our knowledge, no population-based study has analyzed the relationship of low birth weight to pRNFL thickness in adulthood. The purpose of this study was to investigate whether birth weight has a long-term effect on pRNFL thickness in adulthood.

Methods

In the German population-based Gutenberg Health Study (GHS), participants were examined with spectral-domain optical coherence tomography using a peripapillary scan and automated measurement of pRNFL thickness as a global parameter and in six sectors. The association between self-reported birth weight and the different pRNFL sectors were anal

SUBMITTER: Fieß A 

PROVIDER: S-EPMC7425698 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature