Task-evoked activity quenches neural correlations and variability across cortical areas.

ABSTRACT: Many large-scale functional connectivity studies have emphasized the importance of communication through increased inter-region correlations during task states. In contrast, local circuit studies have demonstrated that task states primarily reduce correlations among pairs of neurons, likely enhancing their information coding by suppressing shared spontaneous activity. Here we sought to adjudicate between these conflicting perspectives, assessing whether co-active brain regions during task states tend to increase or decrease their correlations. We found that variability and correlations primarily decrease across a variety of cortical regions in two highly distinct data sets: non-human primate spiking data and human functional magnetic resonance imaging data. Moreover, this observed variabil

SUBMITTER: Ito T 

PROVIDER: S-EPMC7425988 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature