Opioid agonist treatment and fatal overdose risk in a state-wide US population receiving opioid use disorder services.

ABSTRACT:

Background and aims

Evidence from randomized controlled trials establishes that medication treatment with methadone and buprenorphine reduces opioid use and improves treatment retention. However, little is known about the role of such medications compared with non-medication treatments in mitigating overdose risk among US patient populations receiving treatment in usual care settings. This study compared overdose mortality among those in medication versus non-medication treatments in specialty care settings.

Design

Retrospective cohort study using state-wide treatment data linked to death records. Survival analysis was used to analyze data in a time-to-event framework.

Setting

Services delivered by 757 providers in publicly funded out-patient specialty treatment progr

SUBMITTER: Krawczyk N 

PROVIDER: S-EPMC7426244 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature