A stepwise titration protocol for oral appliance therapy in positional obstructive sleep apnea patients: proof of concept.

ABSTRACT:

Purpose

In patients with positional obstructive sleep apnea (POSA), oral appliance therapy (OAT) is among the first-line treatments. The aim of this study was to evaluate the effects of a new standardized stepwise titration protocol for OAT in a group of patients with POSA.

Methods

This was an observational intervention trial. Patients who were previously randomized to the OAT intervention arm of a comparison study comprised the subjects for this study. These patients, who had mild to moderate POSA, were assessed after 3 and 12 months for treatment efficacy, objective adherence by temperature microsensor, and side effects. The titration of OAT was performed using a standardized stepwise titration protocol including advancement levels of 60%, 75%, and 90% of the maximum mandi

SUBMITTER: de Ruiter MHT 

PROVIDER: S-EPMC7426292 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature