Motivation for and adherence to growth hormone replacement therapy in adults with hypopituitarism: the patients' perspective.

ABSTRACT:

Introduction

While reasons for non-adherence in children requiring growth hormone (GH) replacement (GH-Rx) are well researched, few studies have investigated adherence in adult GH deficient patients. Against the background of the adverse medical sequelae of untreated severe GH deficiency (GHD) in adults, we explored adherence to GH-Rx and associated factors in this patient group.

Method

Cross-sectional analysis including 107 adult patients with severe GHD on GH-Rx, 15 untreated GDH patients and 19 who had discontinued therapy. Patients completed self-developed ad hoc surveys on adherence to medication and GH-Rx, specific beliefs about GH-Rx, side effects and burden of injection, reasons for never receiving or dropping out of therapy, respectively.

Results

Adherence to

SUBMITTER: Kreitschmann-Andermahr I 

PROVIDER: S-EPMC7426293 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature