Ontology highlight
ABSTRACT:
SUBMITTER: Sieminska I
PROVIDER: S-EPMC7426395 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Sieminska Izabela I Baran Jarek J
Frontiers in immunology 20200807
Colorectal cancer (CRC) remains one of the most common malignancies diagnosed worldwide. The pathogenesis of CRC is complex and involves, among others, accumulation of genetic predispositions and epigenetic factors, dietary habits, alterations in gut microbiota, and lack of physical activity. A growing body of evidence suggests that immune cells play different roles in CRC, comprising both pro- and anti-tumorigenic functions. Immunosuppression observed during cancer development and progression i ...[more]