Analysis of the prognostic significance of solute carrier (SLC) family 39 genes in breast cancer.

ABSTRACT: Breast cancer (BC) is the most common malignancy in females and remains a main cause of cancer-associated death worldwide. The solute carrier (SLC) groups of membrane transport proteins, which control the influx of zinc, participate in ranging of physiological processes and may provide novel therapeutic targets of cancers. However, the prognostic values of individual SLC family 39 (SLC39A) genes in patients with BC are not clarified. The mRNA expression of SLC family 39 genes in BC was evaluated by using the UALCAN database. The prognostic values of overall survival (OS) of SLC family 39 genes in patients with BC were investigated by Kaplan-Meier plotter. The survival analysis of cells was determined by Project Achilles. The analytic results suggested that SLC39A1, SLC39A3, SLC39A4, SLC39A

SUBMITTER: Liu L 

PROVIDER: S-EPMC7426635 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature