Evaluation of the Cost-effectiveness of Infection Control Strategies to Reduce Hospital-Onset Clostridioides difficile Infection.

ABSTRACT:

Importance

Clostridioides difficile infection is the most common hospital-acquired infection in the United States, yet few studies have evaluated the cost-effectiveness of infection control initiatives targeting C difficile.

Objective

To compare the cost-effectiveness of 9 C difficile single intervention strategies and 8 multi-intervention bundles.

Design, setting, and participants

This economic evaluation was conducted in a simulated 200-bed tertiary, acute care, adult hospital. The study relied on clinical outcomes from a published agent-based simulation model of C difficile transmission. The model included 4 agent types (ie, patients, nurses, physicians, and visitors). Cost and utility estimates were derived from the literature.

Interventions

Daily sporicida

SUBMITTER: Barker AK 

PROVIDER: S-EPMC7426752 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature