Risk factors for anastomotic leakage and its impact on long-term survival in left-sided colorectal cancer surgery.

ABSTRACT:

Background

Anastomotic leakage (AL) significantly impairs short-term outcomes. The impact on the long-term outcomes remains unclear. This study aimed to identify the risk factors for AL and the impact on long-term survival in patients with left-sided colorectal cancer.

Methods

Nine-hundred patients with left-sided colorectal carcinoma who underwent sigmoid or rectal resection were enrolled in the study. Risk factors for AL after sigmoid or rectal resection were identified, and long-term outcomes of patients with and without AL were compared.

Results

AL rates following sigmoid and rectal resection were 5.1% and 10.7%, respectively. Higher ASA score (III-IV; OR = 10.54, p = 0.007) was associated with AL in patients undergoing sigmoid surgery on multivariable analysis. M

SUBMITTER: Kryzauskas M 

PROVIDER: S-EPMC7427291 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature