New Opioid Use after Invasive Mechanical Ventilation and Hospital Discharge.

ABSTRACT: Rationale: Patients who receive invasive mechanical ventilation (IMV) are usually exposed to opioids as part of their sedation regimen. The rates of posthospital prescribing of opioids are unknown.Objectives: To determine the frequency of persistent posthospital opioid use among patients who received IMV.Methods: We assessed opioid-naive adults who were admitted to an ICU, received IMV, and survived at least 7 days after hospital discharge in Ontario, Canada over a 26-month period (February, 2013 through March, 2015). The primary outcome was new, persistent opioid use during the year after discharge. We assessed factors associated with persistent use by multivariable logistic regression. Patients receiving IMV were also compared with matched hospitalized patients who d

SUBMITTER: Wunsch H 

PROVIDER: S-EPMC7427379 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature