Molecular epidemiology of carbapenemase-producing Enterobacterales in Finland, 2012-2018.

ABSTRACT: Carbapenemase-producing Enterobacterales (CPE) pose an increasing threat to patient safety and healthcare systems globally. We present molecular epidemiology of CPE in Finland during 2012-2018 with detailed characteristics of CPE strains causing clusters during the same time period. All Finnish clinical microbiology laboratories send Enterobacterales isolates with reduced susceptibility to carbapenems or isolates producing carbapenemase to the reference laboratory for further characterization by whole genome sequencing (WGS). In total, 231 CPE strains from 202 patients were identified during 2012-2018. Of the strains, 59% were found by screening and 32% from clinical specimens, the latter were most commonly urine. Travel and/or hospitalization history abroad was reported for 108/171 strain

SUBMITTER: Raisanen K 

PROVIDER: S-EPMC7427707 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature